Matti Pitkänen (matpitka@pcu.helsinki.fi)
Wed, 1 Dec 1999 10:19:39 +0200
Below is the slightly corrected version of previous message, which contained
stupid error (comment about chess).
****************************************************************************************
Hi all,
 
Yesterday I ended up with a quantitative prediction about evolution
made possible by the identification  of evolution as  p-adic evolution.
Before continuing:
 
a)   Does anyone know   estimate for the neuron 
number for the largest structural units  of  the 
most primitive  vertebrate brains? My rough 
estimate is that neuron number  N=256.000 is a good order of magnitude guess
for the emergence of cognition and possibly of vertebrates with their
brains increasing rapidly in size.   I could not however
find from web any data about this and  I have no access to literature.
 
b) Does anyone know whether cortex contains  modular
cubical structures  such that the side of cube is 4 mm?
Cubes of this side should combine to form  cubes/ bilayers with 
side/thickness  8 mm.  This should be largest modular structure 
repeating itself in human brain. Any information?
 
Below brief exposition of evolution understood as p-adic evolution.
   1. Evolution as p-adic evolution
Quantum TGD predicts that evolution reduces to
the gradual increase of p-adic prime  characterizing
spacetime sheet  of biostructure.
Each revolutionary step corresponds to the emergence
of a new larger p-adic   spacetime sheet containing
earlier structures and having    minimal size
characterized by p-adic length scale  L_p:
L_p= about sqrt(p)*10^4 Planck lengths,
p =about 2^k, k prime of  power of prime.
There are  not two many interesting values of k in biolength scales.
a) Below neúron length scale k=167 the interesting p-adic primes
correspomd to  
 
k=137,139, k=149,151, k=163 and k=167.
 
b)  Above neuron length scale one has  primes 
k= 169=13^2, 173, 179, 181,191,193, 197, 199, 211, 223,..
 
 
2. Preneural evolution
There are several revolutions preceding the emergence of
cell. The levels preceiding cellular evolution correspond to
 
k=137,139: DNA and DNA double helix. k=137 corresponds to
atomic length scale.
k=149,151: lipid layers of cell membrane and cell membrane itself. 
 
k=157 and k=163: L(157) correponds to 80 nanometers.
L(163) corresponds to length scale .64 micrometers.
My poor knowledge about cell biology does not allow  clearcut
interpretation. Some cell organelles. Nucleus, ribosomes? 
Collagen fibres forming the connective tissue of body and
giving rise to body consciousness?  Can anyone  help? 
. 
3.  Evolutionary steps at critical neuron numbers
This leads to a precise prediction at what critical neuron numbers
evolution of nervous system made dramatic jumps.
Since typical cell size  corresponds to the length scale L(k=167),
these jumps occurred when the neuron number  for relevant
unit of brain became so large that neurons filled  volume of  cube
with side L(k). Thus the critical neuron numbers
are given by
N(k) =about (L(k)/L(167)^3  .
If one considers spheres of diameter L(k), the estimate is reduced by
a factor of 1/2.
More concretely, for *cube topology* critical neuron numbers
with suggested evolutionay interpretation  are
a) N(169)= 8: epithelial sheets: organs, skin, walls for the nuclei of brain. 
Primary sensory experience?
 
b) N(173)= 512:   Larger structures in midbrain consisting of cubes containing  8x8x8 
cells. 3-dimensional chess-board or 8-move simulation for ordinary chess game. 
Perhaps the structure of chess game is not an accident but reflects the 
basic morphology of brain.  Does these structures make emotions possible? 
Is Cambrian explosion related to this length scale. Neuron number for nematode worm 
is about 300. Prediction is   consistent with Hameroff-Penrose prediction 
(if structure was spherical, N(173)= about 256).
c) N(179)=about 256.000: Ocular dominance columns in cortex and similar
structures. Emergence of cognition?   Emergence of  vertebrates? 
 
N(181)= 8*N(179): Pairs of ocular dominances columns correspond to k=181. 
Integration of left and  right cognition to stereocognition, say stereovision.
d)  N(191)= (2^18)*N(179). Structures of size 1/2 mm.
N(193)= 2^3* N(191). Cubical structures  of side 1 mm.  The morphology
of cortex demonstrates decomposition to modules of size (1 mm)^3.
These structures should consist of  8  sub-cubes of side 1/2 mm!
Some kind of comparison modules, novelty detectors?
e)  k=197 and 199 form again a pair. Does anyone know 
about the  structure  of the human brain in these length 
scales? Is this the level of cognition, which is especially
evolved in the brain   of  chess-players?
f)  k=211: L(211) corresponds to 24 cm length scale. This length scale 
seems to  be larger than the  size of  human brain. 
Thus, possibly apart from k= 197 case,   it seems that p-adic TGD is consistent
with the architecture   of  brain correctly!  Comments?
  
Best,
MP
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