Matti Pitkänen (matpitka@pcu.helsinki.fi)
Sat, 4 Dec 1999 11:04:47 +0200
Hi all.
The problem of how genetic code codes the structure
of body and how genetic is physically expressed is one
of the great puzzles of biology. Related puzzle is
differentiation of cells. There is also the problem of
junk DNA: only 10 per cent of DNA actually codes proteins.
The reason why these problems seem so untractable might be
due to the wrong view about spacetime. Manysheeted spacetime
concept might be absolutely crucial for the expression of genetic
code. DNA itself might involve many-sheeted spacetime structures
coding faithfylly the topology of the body parts.
This manysheeted structure of DNA could allow to understand the
the miraculous looking features
of DNA replication (for instance, how the coding of
RNA starts on correct position) and differentiation of cells.
\vm
1. How the morphology of body is coded?
The first question is how DNA codes the morphology of body.
The crucial observationis following:
*Total length of DNA is of same order of magnitude as the size
of body*.
This suggests that the information coded by
DNA is about one-dimensional skeleton of body part with
transverse dimensions code to point.
According to work of Mae-Wan Ho, living systems are liquid crystals.
Liquid crystals are effectively one-dimensional since the
layers of the liquid crystal consist of homogenous liquid phase determined
by macroscopic characteristics such as pH, temperature, ionic concentrations
and electric fields. Therefore the information coded to DNA would
be essentially information about the macro properties of the layers
of liquid crystal. This would make 1-dimensional
coding of the body plan using DNA sequences very natural.
Kind of contraction of the
body parts to DNA sequences having manysheeted structure
could be in question! This coding would
preserve the topological structure of the manysheeted
spacetime surface representing part of body.
2. How DNA is expressed?
The second question is how DNA is expressed. The simplest
answer is that body parts contracted to one-dimensional
structures grow to their original shape and size!
During growth various thin spacetime sheets associated
with DNA gradually grow and are glued by join along boundaries
contacts and form the spacetime sheets associated with body
parts! Manysheeted DNA would represent only different phase
of a body contracted to a thin thread: simple!
Of course, things are probably as simple as this.
This simple model however serves as a good
first working hypothesis.
3. What makes differentiation possible?
The third question is how differentiation is possible.
Differentiation must be explainable as a selective activation of
genes so that they are translated to proteins. It could
be that the # contacts (wormhole contacts) from genes to
various spacetime sheets representing body parts serve provide the
interaction with the classical fields of the macroscopic spacetime
sheets representing body arts and controlling the activity of particular
DNA. Eectromagnetic oscillation frequencies could
be in question. In absence/presence of oscillation gene is
activated. This picture could also solve the problem of junk DNA.
Perhaos junk DNA does not have wormhole
any contacts to any spaceetime sheets
representing body and is not therefore activated at any stage
of growth.
Best,
MP
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